Ginkgo Biloba has been used for thousands of years in traditional folk medicine. Today, it is one of the most important plants in phytotherapy. It enhances performance, memory, and reactivity, among other things, through improved blood circulation in the brain. As a result, cells receive better oxygen and nutrient supply, which helps boost the functions of the body and the brain.

The psychopharmacological effects of Ginkgo biloba extract innormal healthy
volunteers
Subhan Z, Hindmarch I.
Int J Clin Pharmacol Res. 1984;4(2):89-93.
Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/6469442
 

[Activity of Ginkgo biloba extract on short-term memory].
Hindmarch I.
Presse Med. 1986 Sep 25;15(31):1592-4.
Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/2947108
 

The dose-dependent cognitive effects of acuteadministration of Ginkgo biloba to healthy young volunteers.
Kennedy DO, Scholey AB, Wesnes KA.
Psychopharmacology (Berl). 2000 Sep;151(4):416-23.
Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/11026748
 

The therapeutic effect of Ginkgo biloba extract in SHRrats and its possible mechanisms based on cerebral microvascularflow and vasomotion.
Zhang J, Fu S, Liu S, Mao T, Xiu R.
Clin Hemorheol Microcirc. 2000;23(2-4):133-8.
Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/11321432
 

Acute, dose-dependent cognitive effects of Ginkgo biloba,Panax ginseng and their combination in healthy young volunteers:differential interactions with cognitive demand.
Scholey AB, Kennedy DO.
Hum Psychopharmacol. 2002 Jan;17(1):35-44.
Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/12404705
 

Neuromodulatory property of standardized extract Ginkgobiloba L. (EGb 761) on memory: behavioral and molecular evidence.
Oliveira DR, Sanada PF, Saragossa Filho AC, Innocenti LR,Oler G, Cerutti JM, Cerutti SM.
Brain Res. 2009 May 7;1269:68-89.
Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/19146837
 

The memory enhancing effects of a Ginkgo biloba/Panaxginseng combination in healthy middle-aged volunteers.
Wesnes KA, Ward T, McGinty A, Petrini O.
Psychopharmacology (Berl). 2000 Nov;152(4):353-61.
Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/11140327
 

Ginkgo biloba for antidepressant-induced sexualdysfunction.
Cohen AJ, Bartlik B.
J Sex Marital Ther. 1998 Apr-Jun;24(2):139-43.
Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/9611693
 

Effects of Ginkgo biloba on mental functioning in healthyvolunteers.
Cieza A, Maier P, Pöppel E.
Arch Med Res. 2003 Sep-Oct;34(5):373-81.
Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/14602503
 
10. Anti-stress effects of Ginkgo biloba and Panax ginseng: acomparative study.
Rai D, Bhatia G, Sen T, Palit G.
J Pharmacol Sci. 2003 Dec;93(4):458-64.
Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/14737017
 

[Value of standardized Ginkgo biloba extract (EGb 761) inthe management of congestive symptoms of premenstrual syndrome].
Tamborini A, Taurelle R.
Rev Fr Gynecol Obstet. 1993 Jul-Sep;88(7-9):447-57.
Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/8235261
 

A double-blind, placebo controlled study of Ginkgo bilobaextract ('tanakan') in elderly outpatients with mild to moderatememory impairment.
Rai GS, Shovlin C, Wesnes KA.
Curr Med Res Opin. 1991;12(6):350-5.
Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/2044394
 

Ginkgo biloba for cerebral insufficiency.
Kleijnen J, Knipschild P.
Br J Clin Pharmacol. 1992 Oct;34(4):352-8.
Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/1457269
 

Effect of two doses of ginkgo biloba extract (EGb 761) onthe dual-coding test in elderly subjects.
Allain H, Raoul P, Lieury A, LeCoz F, Gandon JM, d'Arbigny P.
Clin Ther. 1993 May-Jun;15(3):549-58.
Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/8364946

The richness of guarana in caffeine provides an almost immediate energy boost. Guarana also contains tannins to which caffeine binds, prolonging the release of caffeine in the body, thereby increasing the duration of the energy boost.

Enhanced Cardiovascular Protection
The work of the heart is facilitated by the vasodilator polyphenols contained in guarana, which counteract the harmful effects of caffeine.

Positive Effects on the Brain
Guarana has a positive effect on brain fatigue and protects the nervous system and brain from degeneration.

Guarana´s Journey from Regional Tonic to Aphrodisiac and GlobalEnergy Drink.
Nigel Smith and Andre Luiz Atroch
Evid Based Complement Alternat Med. 2010 Sep;7(3):279-82.
PMC: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887323/
 

A double-blind, placebo-controlled, multi-dose evaluationof the acute behavioural effects of guaraná in humans.
Haskell CF, Kennedy DO, Wesnes KA, Milne AL, Scholey AB.
J Psychopharmacol. 2007 Jan;21(1):65-70. Epub 2006 Mar 13.
Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/16533867
 

Acute effects of guarana (Paullinia cupana Mart.) on mousebehaviour in forced swimming and open field tests.
Campos AR, Barros AI, Albuquerque FA, M Leal LK, Rao VS.
Phytother Res. 2005 May;19(5):441-3.
Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/16106397
 

Improved cognitive performance in human volunteersfollowing administration of guarana (Paullinia cupana) extract:comparison and interaction with Panax ginseng.
Kennedy DO, Haskell CF, Wesnes KA, Scholey AB.
Pharmacol Biochem Behav. 2004 Nov;79(3):401-11.
Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/15582012
 

Improved cognitive performance and mental fatiguefollowing a multi-vitamin and mineral supplement with added guaraná(Paullinia cupana).
Kennedy DO, Haskell CF, Robertson B, Reay J, Brewster-MaundC, Luedemann J, Maggini S, Ruf M, Zangara A, Scholey AB.
Appetite. 2008 Mar-May;50(2-3):506-13. Epub 2007 Oct 30.
Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/18077056
 

Effect of lyophilized extracts from guaraná seeds[Paullinia cupana var. sorbilis (Mart.) Ducke] on behavioralprofiles in rats.
Otobone FJ, Sanches AC, Nagae R, Martins JV, Sela VR, deMello JC, Audi EA.
Phytother Res. 2007 Jun;21(6):531-5.
Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/17397119